Totally Drug-Resistant TB at Large in India

Andy Coghlan, New Scientist, January 12, 2012

A strain of tuberculosis that is resistant to all existing TB drugs has emerged in Mumbai, India.

“We currently have 12 confirmed cases, of which three are dead,” says Zarir Udwadia of the Hinduja National Hospital and Medical Research Centre in Mumbai, and head of the team whose diagnoses of four cases has just been published.

The emergence of the disease in such a densely populated city is a major concern as it could spread so easily. “We know one patient transmitted it to her daughter,” Udwadia told New Scientist. “It’s estimated that on average, a tuberculosis patient infects 10 to 20 contacts in a year, and there’s no reason to suspect that this strain is any less transmissible,” he warns.

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